GINOP-2.3.2-15-2016-00048 – STAY ALIVE

Project Title: Improving Severity and Mortality Indicators of Life-Threatening Acute Conditions through Translational Medical Approaches

Funding Rate: 100%

Total Funding: HUF 1,494,053,285

PTE Share: HUF 886,027,788

Start: 2017.02.01. | End: 2021.05.01.

Consortium Leader: University of Pécs

Consortium Members: University of Debrecen, University of Szeged

Project Manager: Csilla Gayár (gayar.csilla@pte.hu)

Scientific Leader: Dr. Péter Hegyi (hegyi.peter@pte.hu)

Project Summary

The project aims to reduce the mortality rate of life-threatening acute conditions using translational medicine. Key research areas include acute pancreatitis, stroke, and heart failure. Basic and clinical researchers collaborate to ensure real-world impact.

Key Focus Areas

• Pancreatology: Studies on cell necrosis, ATP supplementation, and clinical trials (GOULASH, PREPAST, etc.)
• Stroke: Research on oxidative stress, neuroprotection, and genetic factors
• Heart Failure: Experimental and clinical research including the RAFFLE registry
• Core Facilities: Patient registries, economic analysis, and the Translational Endoscopy Center

Results and Progress (Year 2–3)

• Over 4,000 patients registered across conditions
• International cooperation expanded (400+ institutions)
• COVID-19 task force (KETLAK) established
• Multiple prospective observational clinical studies launched

EFOP-3.6.2-16-2017-00006 – LIVE LONGER

Project Title: Development of Modern Medical Diagnostics and Therapies Using Translational Approaches – From Laboratory to Bedside

Funding Rate: 100% | Total Funding: HUF 1,463,467,708

Duration: 2017.09.01. – 2020.11.29.

Main Beneficiary: University of Szeged

Consortium Members: University of Debrecen, University of Pécs, Semmelweis University

Project Manager: Anikó Zsigmond | Financial Lead: Ágnes Harmati-Major | Scientific Lead: Prof. Dr. Zoltán Rakonczay

Project Objectives

The project aims to improve quality of life and longevity for patients with gastrointestinal, cardiac, vascular, and musculoskeletal diseases. It spans the full spectrum of biomedical research, from molecular biology to applied therapies, based on inter-university collaboration.

Research Focus Areas

• Cardiology: Studies on arrhythmia, heart failure, and experimental models
• Gastroenterology: Research on pancreatic development, CFTR, organoid biobanks, GI motility, PSC, and more
• Vascular System: Investigations into TRPM4, RAAS, phosphate transporters, and vascular remodeling
• Muscle Research: Studies on calcium handling, metabolism during pregnancy, aging (sarcopenia), and obesity