PPDM

Post-pancreatitis diabetes mellitus (PPDM) is a common complication of chronic pancreatitis (CP) and occurs in up to 80% of patients during the course of CP. Patients with PPDM are often misdiagnosed and treated as type 2 diabetics. This is problematic, as PPDM has a specific pathophysiology and clinical presentation: patients often suffer from "brittle diabetes", characterised by fluctuating blood glucose levels, frequent hypoglycaemic episodes and poor glycaemic control.

This study will investigate the variability of the course of diabetes with a diagnosis of CP, and by processing the data will provide novel information on the variability of glucose levels and the frequency of hypoglycaemic episodes in patients with PPDM. This information will help to establish an accurate prognosis of the disease and identify relevant targets for treatment.

Aim of the study:

- To investigate the risk factors for hypoglycaemia.

- To assess awareness of hypoglycaemia using the Clarke Hypoglycaemia Assessment Test.

- To assess the proportion of patients with ketoacidosis in the previous 12 months

Principal investigator: Prof. Dr. Péter Hegyi

Local coordinator: Zoltán Hajnády