CP Registry

CP Registry

Gastroenterology

Chronic pancreatitis (CP) is the chronic inflammation of the pancreas that causes progressive and permanent organ damage. The annual incidence of chronic pancreatitis is 2 to 23 per 100,000 persons. Its prevalence is still increasing, which is mostly attributed to lifestyle factors like alcohol abuse or smoking. Although the disease is mostly treated in outpatient care, there are several patients requiring urgent hospital admission. Because of the complex pathogenesis and the severe clinical course, chronic pancreatitis imposes a great burden on healthcare and society. 

Chronic Pancreatitis in 2020

• CP represents a disease continuum. Improved non-invasive and endoscopic imaging enabled better recognition of incipient morphological and functional changes in the pancreas, but validated criteria for diagnosing early-stage CP are still lacking.

• Chronic pancreatitis has a significant impact on patients’ life. In most cases, the main symptoms are pain, digestive disorders and weight loss, which significantly worsen quality of life. Current management of CP is limited to the symptomatic treatment of its clinical manifestations, evidence-based therapeutic approaches are still missing.

• The discovery that hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene (PRSS1) in 1996 provided a conceptual breakthrough. Since then, several other genes have been implicated that predispose to CP. In spite of the evidence, genetic testing is not performed in many parts of the world.

Future challenges and opportunities

• By using the approach of translational medicine, animal model discoveries of the pathogenesis should be translated into curative or preventive interventions.

• A standard follow-up management should be developed to identify the complications in time.

• Simpler, less-invasive screening tools should be developed to measure acinar and ductal cell function from biological specimens that are easily obtainable such as urine or blood.

• Evidence-based lifestyle recommendations should be made.

The CP registry has been set up to collect data regarding current practices of diagnosis and treatment and to carry out genetic analysis to discover new predisposing genetic mutations. Since it is a chronic disease, it is crucial to follow-up patients and involve them in clinical trials in order to gain an insight into (1) disease progression, (2) its influence on quality of life and (3) the effectiveness of available therapies. 

Uploading centres

 PTE Klinikai Központ: 171

  • Clinicians: Judit Bajor, József Czimmer, Bálint Erőss, Szilárd Gódi, Péter Hegyi, Péter Kenyeres, Katalin Márta, Alexandra Mikó, Andrea Párniczky, Dániel Pécsi, Imre Szabó, Áron Vincze, Eszter Hegyi, Márk Félix Juhász, Klementina Ocskay, Péter Hegyi, Szilárd Váncsa, Dezső Kelemen
  • Administrators: Krisztina Harth, Gréta Szász, Judit Girán, Tímea Mészáros, Vivien Vass, Nikoletta Révész

SZTE Klinikai Központ: 240

  • Clinicians: Dóra Illés, Balázs Kui, Dóra Mosztbacher, Balázs Csaba Németh, Zoltán Szepes, Balázs Koncz
  • Administrators: Anett Lőrincz, Bea Sarnyai, Zsuzsa Égerházi-Molnár, Era Darvasi, Zsuzsanna Répásy, Klaudia Dobai

Fejér Megyei Szent György Kórház: 47

  • Clinicians: Ferenc Izbéki, István Tokodi, Veronika Dunás-Varga
  • Administrators: Erzsébet Jákob, Bettina Varga

Dr. Bugyi István Kórház: 5

  • Clinicians: Barnabás Bod

  • Administrators: Istvánné Pálfia

Országos Onkológiai Intézet: 26

  • Clinicians: Richard Szmola

Bajcsy-Zsilinszky Kórház: 8

  • Clinicians: József Hamvas
  • Administrators: Tünde Kiss

Debreceni Egyetem: 24

  • Clinicians: Eszter Krisztina Fehér, Mária Papp, Tamás Janka
  • Administrators: Zsuzsanna Zádori, Gabriella Terdik

Békés Megyei Pándy Kálmán Kórház: 7

  • Clinicians: János Novák

BMKK Dr. Réthy Pál Kórház: 17

  • Clinicians: Edit Balla, Krisztián Pepa, Márta Varga
  • Administrators: Andrea Katalin Fehér

Heim Pál Kórház: 6

  • Clinicians: Natália Lásztity, Enikő Horváth, Andrea Talabér

B.-A.-Z. Megyei Kórház és Egyetemi Oktató Kórház: 7

  • Clinicians: János Sümegi

Bács-Kiskun Megyei Kórház: 3

  • Clinicians: Zsolt Dubravcsik, István Hritz

Semmelweis Egyetem: 18   

  • Clinicians: Péter Lakatos, Bálint Tél, Árpád Patai, Ákos Szücs

Betegápoló Irgalmasrend Budai Irgalmasrendi Kórház: 4

  • Clinicians: András Gelley

MH Honvédkórház: 3

  • Clinicians: Eszter Schäfer, Tibor Gyökeres   

Csongrád Megyei Egészségügyi Ellátó Központ: 1

  • Clinicians: Csaba Góg

Szabolcs-Szatmár-Bereg Megyei Kórházak és Egyetemi Oktatókórház Jósa András Oktatókórház: 1

  • Clinicians: Ildikó Guthy, László Szegedi

Petz Aladár Megyei Oktató Kórház: 2

OVERALL: 590

Data as of 26. 05. 2021.